Do prohormones affect testosterone?

Prohormones are precursors to hormones and are intended to increase hormone levels like testosterone when taken as supplements. However, their effects on natural testosterone production are complex.
Some key points about prohormones and testosterone:



Common prohormones like androstenedione, 19-norandrostenedione and 1-androstenediol (1-AD) provide testosterone benefits when taken, including:



However, by providing synthetic testosterone levels, they signal the body to stop naturally producing its own testosterone.



Prohormone suppression of natural testosterone depends on factors like:



Strategies to mitigate testosterone suppression include:



With precautions like shorter cycles and proper PCT, temporary testosterone suppression from prohormones can be managed without long-term endocrine dysfunction. However the side effects pose risks and they remain controversial.





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